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Hydroxyapatite, HAP

Formula: [Ca5(OH)(PO4)3]x

CAS No.: 1306-06-5

EC No.: 235-330-6


● Product Description

Hydroxyapatite (HAP), also known as basic calcium phosphate, is the natural mineral form of calcium apatite (Ca5(PO4)3(OH)). As the primary inorganic component of human and animal bones, hydroxyapatite exhibits exceptional biocompatibility and bioactivity. It can chemically bond with surrounding tissues at the interface, gradually release harmless ions into the body with a certain degree of solubility, participate in metabolic processes, stimulate or induce osteogenesis, and ultimately promote the repair of defective tissues.


● Specifications

Form: nanopowder solid

Melting Point: 1100 °C (lit.)

Molecular Weight: 502.31 g/mol


 Product List

Product Name

Particle Size (Diameter)

Nano-Hydroxyapatite (Nano-HAp)

< 0.1 μm

Micron-scale Hydroxyapatite (HAp)

< 20 μm

● Storage

Seal and store in a cool, dry environment; avoid air exposure to prevent moisture absorption, oxidation, and agglomeration that may impair dispersibility and performance. Custom packaging (including aliquoting) available upon request.

● Reference

1.Lee K K, Raja N, Yun H, et al. Multifunctional bone substitute using carbon dot and 3D printed calcium-deficient hydroxyapatite scaffolds for osteoclast inhibition and fluorescence imaging. Acta Biomaterialia, 2023, 159: 382-393.

2.Mashak A, Bazraee S, Mobedi H. Advances in drug delivery and biomedical applications of hydroxyapatite-based systems: a review[J]. Bulletin of Materials Science, 2022, 45(4): 183.

3.Zuo S, Peng Q, Luo T, et al. Microwave-assisted synthesis of composites based on titanium and hydroxyapatite for dental implantation[J]. Biomaterials Science, 2024, 12(1): 92-107.


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