Product Overview

Our PLGA microspheres are synthesized from poly(lactide-co-glycolide), a high-performance biodegradable polymer. PLGA is FDA-approved for human use and is widely recognized for its excellent biocompatibility and controllable degradation rates.

Key Features

•Precision Monodispersity: Narrow and controllable particle size distribution.

•Safety & Reliability: Highly safe raw materials requiring no specialized toxicity treatment before use.

•Versatile Payload Delivery: Capable of loading various active pharmaceutical ingredients (APIs), including proteins, peptides, and small molecules.

•Tailored Customization: Available with customized sizes, material ratios (L/G), and surface functionalization to meet specific research needs.

Applications

•Advanced Drug Delivery: Tested for systemic compatibility and used as carriers for controlled, sustained, and targeted delivery.

•Tissue Engineering: Acts as a scaffold for cell seeding and carries bioactive molecules to facilitate the repair or regeneration of tissues and organs.

•Medical Aesthetics: Utilized as injectable fillers for skin tissue, smoothing wrinkles and correcting facial contours.

Product Specifications

•Form: Lyophilized (Freeze-dried) powder

•Packaging: Vials

•Storage: -20°C, protected from light

Note: For research use only.

Custom particle sizes and molecular weights are available upon request.

Resuspension Protocol

For optimal performance of lyophilized microspheres (PLGA/PCL):

Retrieval: Remove the vial from storage.

•Equilibration: Allow the vial to reach room temperature before opening.

•Solvent Addition: Add the required volume of deionized water or buffer.

•Vortexing: Use a vortex mixer to ensure the microspheres are uniformly dispersed.

•Ultrasonication: Place in an ultrasonic bath for 5 minutes to break up any potential aggregates.

•Inspection: Verify the suspension is uniform and free of visible clusters.

References

1.Guo, Xiaoping, et al. PLGA-based micro/nanoparticles: an overview of their applications in respiratory diseases. International Journal of Molecular Sciences. 24.5 (2023): 4333.

2.Yang J, Zeng H, Luo Y, Chen Y, Wang M, Wu C, Hu P. Recent Applications of PLGA in Drug Delivery Systems. Polymers. 2024; 16(18):2606.