Linear Formula: [C3H4O2]x[C2H2O2]y
CAS No.: 26780-50-7
● Product Description
Poly(D,L-lactide-co-glycolide) (PLGA) is a well-established biodegradable copolymer widely studied in biomedical materials research, including drug delivery and resorbable device development. By varying the lactide-to-glycolide ratio, key material properties such as degradation behavior and thermal characteristics can be tailored.
● Specifications
Appearance | white to light tan granules |
Melt Point | amorphous |
Glass transition temperature | 45~50°C |
Soluble in | chloroform, DMSO, dichloromethane, acetone, ethyl acetate, tetrahydrofuran |
| Storage | -15°C, protected from light and moisture |
● Applications
SEM Image of PDLGA Nanofibers
SEM Image of PDLGA Nanoparticles
● Product List
Product Number | Monomer ratio | Inherent viscosity | Mn(g/mol) |
SorlymerTM PDLGA 10 | DL-lactide and glycolide) (50:50) | 0.8-1.2dl/g | 74,000 |
● References
1. Little, H.; Clarke, S. A.; Cunningham, E.; Buchanan, F. Process-induced degradation of bioresorbable PDLGA in bone tissue scaffold production. Journal of Materials Science: Materials in Medicine, 2018, 29(1): 14.
2. Lima L L, Bierhalz A, Moraes N M. Influence of the chemical composition and structure design of electrospun matrices on the release kinetics of Aloe vera extract rich in aloin. Polymer Degradation and Stability, 2020:109233.
3. Far J, El-Haq M A, Gruber M, et al. Developing Biodegradable Nanoparticles Loaded with Mometasone Furoate for Potential Nasal Drug Delivery. ACS Omega, 2020, 5(13):7432-7439.
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