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Polycaprolactone (PCL)

Linear Formula:  (C6H10O2)n

CAS No.: 24980-41-4


Product Description

Polycaprolactone (PCL) is a semi-crystalline, hydrophobic, biodegradable polyester that has gained popularity as a biomedical polymer due to its biocompatibility, ease of manipulation both chemically and physically, and tunable degradation rates. It is a versatile polymer that can be processed into various forms, including films, fibers, and 3D printed scaffolds, making it suitable for a wide range of applications in tissue engineering, and drug delivery.


Specifications

Appearance

White granules

Melt Point:

~ 60 °C

Glass transition temperature

(Tg ~ 60 °C) 

Soluble in

various organic solvents like dichloromethane, benzene, chloroform, toluene and carbon tetrachloride. However, it exhibits limited solubility in acetone, ethyl acetate, dimethylformamide and acetonitrile, while it is insoluble in alcohol, water and diethyl ether 

Storage

 -15°C, protected from light and moisture

Applications

SEM Image of PCL Microspheres

image-(1).jpg


Optical Micrograph of PCL 3D-printed scaffold  

image (3).png


 Product  List

Product Number

Description

Inherent viscosity

SorlymerTM PCL 17

Polycaprolactone 

1.5-1.9 dl/g

SorlymerTM PCL 12

Polycaprolactone 

1.0-1.3 dl/g

SorlymerTM PCL 08

Polycaprolactone 

0.7-0.9 dl/g

SorlymerTM PCL 04

Polycaprolactone 

0.35-0.43 dl/g


 References

[1] Malikmammadov E , Tanir T E , Kiziltay A ,et al.PCL and PCL-Based Materials in Biomedical Applications. Journal of Biomaterials Science Polymer Edition, 2017, 29(7-9):1-55.

[2] Tao X, Zhipeng L, Bin D, et al. Polymer blend nanofibers containing polycaprolactone as biocompatible and biodegradable binding agent to fabricate electrospun three-dimensional scaffolds/structures. Polymer, 2018, 151(29): 299-306.

[3] Duran, M. , et al. Microcapsule production by droplet microfluidics: A review from the material science approach. Materials & Design (2022).

[4] Chen, Philipp W. , R. M. Erb , and Studart, André R. Designer Polymer-Based Microcapsules Made Using Microfluidics. Langmuir the Acs Journal of Surfaces & Colloids 28.1(2012):144.


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